Participate in Clinical Research

Date posted: June 5, 2025

Relative Diversity associated with Neurexin Trajectories (RaDiaNT)

Study description:

The RaDiaNT study led by the BEACON Research Group at SickKids, and aims to better understand the effects of NRXN1 deletions. These genetic changes can cause developmental and neurological differences, however, not all individuals with the deletion develop these conditions. The study will explore how genetic, environmental, and lifestyle factors contribute to the different outcomes observed in individuals with this deletion. We aim to understand why these outcomes differ, even among family members.

Benefits to participating:

Participants will receive a gift certificate, volunteer hours and reimbursement for parking/TTC costs.

Enrolling:

Open, Healthy volunteers

Who can participate:

We are looking for individuals who have a confirmed diagnosis of NRXN 1 Deletion and their family members (parents/siblings) with or without NRXN 1 Deletion 

We are also looking for individuals between the ages of 3 to 21 years old with no history or close family history of a neurodevelopmental or mental health condition.

What's involved:

Participation in the study will include 2 onsite visits to SickKids or at the participants' homes, each visit being approximately 4 hours long. Participants are to provide a blood or saliva sample, complete questionnaires and interviews about each participant's health, development, behavior, and family history. This can be done either in person or online through a secure system called REDCap or Microsoft Teams. Participants will also watch videos with MEG, EEG, and eye tracking.

Location:

SickKids or participants homes

Principal investigator:

Gallagher, Louise

Official study title:

1000080839 - Relative Diversity associated with Neurexin Trajectories

Interested in participating in this study?

Contact name:

Leanne Ristic

Telephone:

NA

Additional information

Additional information

Additional files for resources: